Product Description: 'The third edition of "The Renal Drug Handbook" is a fantastic publication. Each of us needs to be wary of prescribing for renal patients and this handbook provides a highly practical, user-friendly method of ensuring that appropriate prescriptions are given to patients, whether they have normal renal function, renal impairment, transplants or are receiving renal replacement therapy. In addition, the authors give very helpful information on pharmacokinetics and common indications for the use of each drug described. This information is not available in any other single textbook. It is an invaluable resource for all healthcare professionals but particularly for those involved in the care of renal patients. A copy of the previous editions could be found chained to notes trolleys in all of the wards where renal patients are cared for in my hospital. This third edition is even more comprehensive' - Aine Burns, Consultant Nephrologist, Centre for Nephrology, Royal Free NHS Trust.
Product Description: In biological systems, the normal processes of oxidation (plus a minor contribution from ionising radiation) produce highly reactive free radicals. These can readily react with and damage other molecules. In some cases the body uses free radicals to destroy foreign or unwanted objects, such as in an infection. However, in the wrong place, the body's own cells may become damaged. Should the damage occur to DNA, the result could be cancer. Antioxidants decrease the damage done to cells by reducing oxidants before they can damage the cell. Virtually all studies of mammals have concluded that a restricted calorie diet extends the lifespan of mammals by as much as 100 percent. This remarkable finding suggests that food is actually more damaging than smoking.As food produces free radicals (oxidants) when metabolised, antioxidant-rich diets are thought to stave off the effects of ageing significantly better than diets lacking in antioxidants. The reduced levels of free radicals, resulting from a reduction in their production by metabolism, is thought to be a major cause of the success of caloric restriction in increasing life span. Antioxidants consist of a group of vitamins including vitamin C, vitamin E, selenium and carotenoids, (such as beta-carotene, lycopene, and lutein). This book brings together the latest research in this dynamic field.
Amazon.comInterest in and usage of herbal preparations as alternatives to pharmaceuticals has exploded in recent years. Having a complete herbal reference on hand is now absolutely necessary for doctors and other healers when a patient wants to add herbs--let's say St. John's wort--to his drug regimen. Should the patient stop taking the Paxil he's been on for depression, and if so, how long must he wait before he can start taking the St. Johns wort, and what's the recommended dosage?
The PDRfor Herbal Medicines will go a long way towards answering such questions. The physician in this case would learn, after consulting the PDR, that "St. John's wort taken concomitantly with an SSRI ... may lead to an increased effect and possible toxicity 'serotonin syndrome', e.g., sweating, tremor, flushing, confusion and agitation." The same physician will also learn that the German Federal Health Authority's Commission E, which has studied the effects of hundreds of herbs, approved St. John's wort for depressive moods, among other conditions.
For more information, the physician can read about the trade names, descriptions of all the medicinal parts of the plant, actions and pharmacology (including the compounds and their effects,with citations), the results of clinical trials, contraindications, precautions and adverse reactions (photosensitization is a biggie for St. John's wort), dosage information, and a complete list of literature citations.
The second edition of thismammoth guide includes over 100 entries more than the first, bringing the total to more than 700. Additions include a selection of Asian herbs, such as Buplerum Chinese (also known as Chinese thoroughwax), which is used in Chinese medicine as an anti-inflammatory, and homeopathic preparations; a directory of manufacturers (with Internet addresses when available), a safety guide (don't use kava kava while nursing), and more. There's even a section that lists unproven uses for each herb. But make no mistake: this is a mainstream reference that relies on scientific proof above all. Therefore, this is not a guide for everyone, but for scientific and medical reference, it's a helpful and comprehensive resource, and even those who push the herbal envelope will find much valuable information here. --Stefanie DurbinBook DescriptionNew, Expanded, Improved, Comprehensive
Building on its best-selling predecessors, the new PDR for Herbal Medicines, Third Edition has left no resource unturned to bring together the latest scientific data in the most comprehensive herbal reference compiled.
The third edition goes far beyond the original source, adding a new section on Nutritional Supplements and new information aimed at greatly enhancingpatient management by medical practitioners. All monographs have been updated to include recent scientific findings on efficacy, safety and potential interactions; clinical trials (including abstracts); case reports; and meta-analysis results. This new information has resulted in greatly expanded Effects, Contraindications, Precautions and Adverse Reactions, and Dosage sections of each monograph.
The most trusted and up-to-date pharmacology text in medicine — completely redesigned to make the learning process even more interesting and efficient Organized to reflect the syllabi in Pharmacology courses, Basic & Clinical Pharmacology covers all the important concepts students need to know about the science of pharmacology and its application to clinical practice. It is acknowledged worldwide as the field’s most current, authoritative, and comprehensive textbook. To be as clinically-relevant as possible, the book features a strong focus on the choice and use of drugs in patients and the monitoring of their effects.
Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference systematically treats the drug development aspects of all human nuclear receptors, including recently characterized receptors such as PPAR, FXR and LXR. Authors from leading pharmaceutical companies around the world present examples and real-life data from their own work.
During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.
Providing an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development, this book equips drug development scientists with an interdisciplinary understanding of these receptors and how to regulate them. This aids in pharmaceutical research to target drugs and treat diseases like cancer, coronary heart disease, and diabetes. A single source for researchers, this book collects material otherwise scattered among journals, and adds background and applications data to make the chapters more comprehensive.
This comprehensive reference guide describes more than 130 alphabetically arranged drugs of abuse, including both pharmaceutical and natural products. The book begins with a discussion of federal drug scheduling and drug categories. Individual entries for particular substances of abuse follow. Drug descriptions include: correct pronunciation, nicknames or street names, legal status, historical and present uses and misuses, abuse factors, interactions with other drugs, and findings of cancer risks and birth defects. Scientific information is presented in a clear, simple manner designed for students and general readers alike. In addition to the A-Z descriptions, Miller provides an explanation of general drug types, such as stimulants and hallucinogens, as well as the aspects of drug abuse, including tolerance and withdrawal. A list of print and electronic sources is also included for readers seeking further information.
Stahl's Essential Psychopharmacology has established itself as the preeminent source of education and information in its field. This much expanded second edition enlists advances in neurobiology, and recent clinical developments, to explain with renewed clarity the concepts underlying drug treatment of psychiatric disorders. New neurotransmitter systems, new theories on schizophrenia, clinical advances in antipsychotic and antidepressant therapy, new coverage of attention deficit disorder, sleep disorders and drug abuse, and a new chapter on gender and sexual psychopharmacology - these are all features of this edition. The fully revised text is complemented by many new illustrations, instructive and entertaining as before, and enhanced to reflect new knowledge and topics covered for the first time. The illustrations and their captions may be used independently of the main text for a rapid introduction to the field or for review, and self-assessment tests follow each chapter. Even more, this will be the essential text for students, scientists, psychiatrists and other mental health professionals, enabling them to master the complexities of psychopharmacology, and plan sound treatment approaches based on current knowledge.
Offers an introduction and revision to the principles of pharmacology. This book presents schematic diagrams and explanations as to how the drugs produce their effects and an outline of their uses. It is suitable for students, junior doctors and scientists requiring an account of medical pharmacology.
